Per a Deloitte (2025) report, millennials and Gen Z report that while a good salary is important, "so is finding meaningful work and well-being" (p. 2 ). In this session presenters will address meaning in work and life in relation to fulfillment, well-being (UNSDG 3), and decent work (UNSDG 8). The session will introduce four papers, five speakers, and one discussant from varied disciplines in social psychology, organizational psychology, cognitive psychology, and international business & management, using varied samples, to address the topic (consistent with AOP DOI 2 and 6). First, Karl will address meta-analytic findings on meaning in life and work-related wellbeing. In the next presentation, Glazer will show how meaningfulness in life protects working mothers who care for critically ill children from experiencing work-related anxiety. Dryjanska will then share qualitative interview findings demonstrating meaning in work as a calling for caregivers of Alzheimer's patients. Finally, Fisher and Cedeño will present results from United States, Germany, Colombia, and South Africa on the different ways in which meaningful work is perceived across cultures and how culture influences the relationship between meaningful work, decent work and well-being. Ji will then provide a critical synthesis of the session and suggest how the scientific findings can be used to guide interventions that help people reframe experiences to mitigate the intensity of the response (consistent with AOP DOI 8 and 9).