Nuclear medicine professionals face exceptional workplace demands characterized by high-stakes precision requirements, prolonged work in confined spaces, and the need to maintain specialized technical expertise. These unique stressors—cognitive load from precision tasks, physical workspace constraints, and constant upskilling pressures—create significant challenges for practitioners' well-being and patient safety. The field's distinctive nature, involving complex radiation safety protocols and advanced imaging/therapeutic procedures, compounds these pressures beyond typical healthcare stressors. This review synthesizes evidence on resilience-building approaches tailored for nuclear medicine practice, drawing from occupational health, human factors engineering, and radiology literature. We analyze three key intervention domains: cognitive-behavioral strategies for precision-related stress, ergonomic adaptations for confined workspaces, and support systems for technical skill maintenance. Findings reveal that effective resilience requires integrated individual, team, and institutional approaches, with notable gaps in practical implementation within nuclear medicine workflows.We propose a multi-level resilience framework addressing: (1) individual techniques for decision fatigue management, (2) workspace innovations like modular equipment redesign, and (3) institutional policies including structured microbreaks and peer support systems. The framework aligns with Sustainable Development Goals by enhancing worker well-being (SDG-3), promoting decent work conditions (SDG-8), and advancing medical technology (SDG-9).
Critical research priorities include developing nuclear medicine-specific resilience metrics and evaluating workspace intervention cost-effectiveness. This review bridges theory and practice, offering actionable insights for healthcare leaders and practitioners to address the field's unique challenges while maintaining high-quality patient care.