Artificial intelligence and use of digital health apps is expanding rapidly in integrated healthcare. The apps range from virtual counselors based on evidence-based practices, intelligent conversational agents (e.g., chatbots) to virtual reality apps to aid in the treatment of mental health and health problems. This presentation will discuss the state of the art of these apps, how they can be implemented into clinical practice and limitations to consider in their use. In addition, the session will discuss the potential advantages for increasing access to mental and behavioral health care. In the last ten years, both the emergence and utilization of artificial intelligence (AI) tools such as intelligent virtual agents (IVAs) and nonembodied conversational agents (CAs), including chatbots, as well as their use in behavioral and mental healthcare, has rapidly expanded (Holohan & Fiske, 2021). Artificial intelligence (AI) is a rapidly growing field that aims to replicate human cognitive abilities such as perception, reasoning, and problem-solving (Abd-alrazaq et al., 2019). It has garnered significant attention in clinical applications and extends beyond conventional statistical methods to extract relevant information that supports decision-making and research (Abd-alrazaq et al., 2019). More specifically, we are observing these systems administer treatment modalities to patients. The integration of AI technology advancement in health care has paved the way for developers to create new and innovative applications to deliver health care resources. Such applications are now made to execute more advanced, diagnostic, analytical, and therapeutic methods as well, which were previously only available from highly qualified healthcare experts. We will focus on the approaches of what powers AI and the implementation of AI in mental health care and how its advancements garnered the potential of implementation of virtual Screening and Brief Intervention for substance use problems. Dr. Bray will discuss applications and limitations to consider in their use.