Emotion regulation is a fundamental psychological process that encompasses both intrapersonal and interpersonal strategies to manage affective experiences. However, the effectiveness of these strategies may be shaped by underlying cognitive-emotional structures developed during early life, such as maladaptive schemas, as well as by meta-emotional belief systems, often referred to as emotion myths. Meanwhile, difficulty in coping with intense internal urges—conceptualized as desire intolerance—has emerged as a transdiagnostic self-regulatory vulnerability. Desire intolerance refers to an individual's perceived inability to endure the internal tension associated with strong desires (e.g., for food, alcohol, or social approval), and is increasingly recognized as a significant component of emotional dysfunction. This study investigates whether emotion regulation strategies mediate the relationship between early maladaptive schemas and desire intolerance, and whether this mediating effect is moderated by the endorsement of rigid emotion-related beliefs. Participants completed a set of validated measures including the Young Schema Questionnaire-Short Form 3 (YSQ-S3), the Emotion Regulation Strategy Scale (ERSS), the Desire Intolerance Questionnaire (DIQ), and the Emotion Beliefs Scale. Although data collection is still ongoing, preliminary findings indicate a significant positive association between early maladaptive schemas and desire intolerance. Initial analyses suggest that emotion regulation strategies may partially mediate this relationship, highlighting their potential role. Moreover, the strength of this indirect effect appears to vary depending on individuals' levels of endorsement of emotion myths; participants with more rigid beliefs about emotions seem to benefit less from adaptive regulation strategies. These findings point to a complex interaction between schema-driven vulnerabilities and regulatory mechanisms, underscoring the value of integrated interventions targeting both early cognitive structures and emotion-related beliefs.