A low level of academic motivation has emerged as a prominent trend among college students. This decline and deterioration in levels of academic motivation have association with two of the most predominant factors: Internet addiction and Substance abuse. Acknowledging these factors and diligently taking measures against them can be pivotal in crafting preventive measures to subdue this maladaptive uprising. Since there as many limitations to the availability of literature in this area of study, a requirement for more extensive research in this area is evident. This chapter delves deep into the understanding and existing standpoint of internet addiction and substance abuse influencing college students towards academic deficits. Scales, including Internet Addiction Test (IAT), Academic Motivation Scale (AMS), and the CRAFFT questionnaire, were administered to 246 students (131 males and 115 females, aged between 18-23 years), and a detailed analysis was formulated. In addition, previous studies from the last 10 years were also referred to for establishing an on-ground understanding. Analysis of the procured data via the scales IAT, AMS & CRAFFT, revealed a significant positive correlation between: internet addiction and substance abuse; internet addiction and multiple motivational dimensions from the CRAFFT questionnaire. The findings of the study suggest: 1) Excessive and unchecked internet use affects cognitive function through reward pathway alterations, attention disruption, and self-regulatory depletion- mechanisms that parallel substance dependencies. 2) An integrative addiction framework recognizing both specific and common etiological pathways between behavioral and substance addictions. Conclusively, the findings have significant implications for developing inhibitory measures to address, prevent, and intervene in students' vulnerability to internet addiction and substance abuse to tackle academic deficits.