Therapists trained in the minority world with Western psychological models often face significant ethical dilemmas when returning to practice in the majority world contexts, where cultural norms and systemic conditions may differ significantly from their training environments. Without a critical lens and intentional decolonization efforts, well-intentioned practices can inadvertently reimpose colonial power dynamics in mental health care. This presentation will build on a recent article, which has been accepted for American Psychologist, that critiques the implicit universality of Western ethical standards and proposes a culturally responsive ethical framework tailored to majority world contexts. Key principles include cultural contextualization, relational ethics, social justice advocacy, integration of Indigenous practices, and reflective practice. Through a detailed case study adapted from a real-life event, the article illustrates the application of this framework for therapists in navigating complex dilemmas that arise at the intersection of cultural dissonance, systemic inequities, and global power dynamics. Recommendations for training programs are provided, emphasizing the integration of international competence, decolonial approaches, and community-based learning to better prepare therapists for culturally attuned and ethically sound practice.