Children of alcoholics (COAs) experience an increased susceptibility to psychological distress, whereas Indigenous adolescents encounter additional vulnerabilities stemming from cultural marginalisation and limited access to mental health services. Culturally appropriate interventions are urgently required in Mizoram, where alcohol misuse has considerable intergenerational consequences. This study developed and evaluated Project VOYAGER, a play-based preventive intervention for Indigenous adolescents aimed at enhancing intrapersonal and interpersonal resilience among Indigenous Mizo children of alcoholics (COAs). Guided by the Broaden-and-Build Theory of Positive Emotions and the Circular Model of Cultural Tailoring, the intervention was implemented in four phases: qualitative needs assessment to identify protective factors among Mizo adult COAs, program development of a 16-session training delivered over four weeks, expert validation, and efficacy testing. The programme focused on intrapersonal skills, interpersonal connection development, and experiential psychoeducation regarding substance use and misuse. A mixed-method research approach was employed and assessed 208 adolescents aged 14 to 17 using the Adolescent Resilience Questionnaire (ARQ). The results indicated substantial enhancements in both individual and peer resilience (p < .05), along with evidence of delayed yet sustained effects on peer relationships. No statistical difference was noted in family, school, or community domains, indicating that extended or family-inclusive formats may enhance outcomes. Project VOYAGER focusses on the potential of culturally tailored play-based approaches to improve resilience in Indigenous Mizo adolescents affected by parental alcoholism. The term "VOYAGER" symbolises a journey, reflecting how the program equips adolescents with skills to navigate adversity and go through adolescence relatively unscathed. The program integrates Indigenous Mizo cultural strengths with positive psychological frameworks, advances emerging trends in applied psychology, provides a robust and contextually relevant model for resilience building, and emphasises avenues for transdisciplinary and community-based prevention strategies.