Artificial Intelligence (AI) is profoundly reshaping human existence, transforming economies, politics, societies, and the very ways we relate to one another, technology, and ourselves. From education and healthcare to interpersonal relationships, AI tools offer remarkable opportunities but also pose significant ethical and anthropological challenges. The development and deployment of these AI technologies is disproportionately controlled by a handful of corporations, which operate with little to no oversight. This concentration of power raises profound concerns about the impact on human dignity, societal structures, and our shared understanding of what it means to be human. In this context, the Catholic notion of subsidiarity emerges as a vital principle by providing a compelling framework for resisting the centralization of technological power. By emphasizing the importance of empowering individuals and communities in their local contexts to make decisions that affect their lives, subsidiarity provides a framework for resisting the centralization of power in the AI landscape. This perspective invites a reimagining of AI governance and application that prioritizes human dignity and the common good. This work draws on research being conducted within the European AI Research Group at the Dicastery for Culture and Education, as well as experiences in Malta involving the practical applications of subsidiarity in addressing AI-related challenges, particularly in education, journalism, and pastoral work. It critically examines how AI technologies shape anthropological perspectives. In doing so, it contributes to the broader task of developing an ethical anthropology based on a contextual approach that can navigate the complexities of the digital age while remaining attentive to the experiences of those on the peripheries of society.