Sentipensar is a Latin American concept that is primarily associated with indigenous traditions of thought. The term is made up of the Spanish words "sentir" (to feel) and "pensar" (to think) and describes an integrative way of thinking that aims to combine body, mind and emotions. Knowledge and action are linked with the mind as well as with feelings and intuition. The concept represents a holistic approach that attempts to overcome the dualistic separation of thinking and feeling. Sentipensar plays a particularly important role in the examination of indigenous knowledge systems and is applied as a critical stance in postcolonial and feminist theory. Knowledge is conceived from a pluralistic perspective. As a concept, Sentipensar has profound relevance for ethics as it brings a holistic, interdisciplinary and intercultural perspective to moral action, decision-making and social justice. It can help to take into account both the rational and the emotional, intuitive and spiritual dimensions of human beings in the field of ethics. The aim is to recognize feelings and emotions as equal sources of moral insight. Consequently, both the cognitive, rational dimensions of moral decisions and the emotional and physical experience of action and compassion are taken into account. This is intended to contribute to an ethics based not only on principles and norms, but also on the concrete, lived experience of compassion, responsibility and the effects of our actions on others. The concept offers a valuable contribution to contextual theology and thus also to ethics, as it goes beyond universalistic statements and includes concrete contexts. The aim of this contribution is to outline the potential and significance of the concept and to bring it into discussion with other approaches as part of a panel discussion.