This paper investigates the conceptual and structural parallels between colonialism and uniatism, positing that both operate as systems of domination and assimilation. Colonialism sought to impose hegemonic cultural, political, and religious frameworks on indigenous populations, often under the pretext of "civilizing" or "elevating" them. Similarly, uniatism, presented as a means to unify separated Christian churches, allowed Eastern Christians to retain their liturgical and cultural practices but placed them within a hierarchical structure subordinated to Roman Catholic authority. While some view this as a preservation of Eastern traditions, others argue it effectively marginalized them, implicitly framing their theology and ecclesiology as incomplete or subordinate. This dynamic pressured Eastern Christianity to conform to Western paradigms, undermining its distinct identity and autonomy. This paper contends that addressing the legacy of uniatism requires more than formal apologies or rhetorical gestures. These actions must be complemented by dismantling lingering hierarchical models and fostering genuine equality. By analyzing historical examples and their present-day implications, this paper advocates for a decolonized ecumenical vision that prioritizes mutual respect, affirms theological plurality, and restores agency to marginalized Christian traditions, challenging the enduring effects of asymmetrical relationships in East-West ecclesial interactions.