In recent years, the global community has faced successive crises in a challenging socioeconomic context. While some crises were unavoidable, others resulted from specific policy decisions and the failure to urgently address climate emergencies. In the summer of 2024, global temperatures reached unprecedented levels, causing extreme weather events like heatwaves, wildfires, floods, and storms, particularly impacting economically disadvantaged and vulnerable communities. These events highlighted deficiencies in social protection and service delivery, worsening existing inequalities and further marginalizing vulnerable populations. Although recovery occurred, it was fragile and unequal, as evidenced by the repeated ineffectiveness of recent Conferences of the Parties (COPs), which fail to establish concrete objectives and actionable plans. Agenda 2030 has raised awareness of environmental, social, and economic emergencies and provided a framework, but it faces criticism for being "too boring" to capture public interest, "too vague" for practical guidance, and "too delayed" to address global challenges adequately. Thus, environmental and global sustainability issues remain unresolved. Environmental sustainability involves conserving natural resources and protecting ecosystems to support health and wellbeing now and in the future. Transdisciplinary and multi-sectoral collaboration in science, policy, and society, summarized in the one health approach, is essential. However, human activities are both the cause of environmental degradation and subject to climate crisis impacts, with spatial heterogeneity adding complexity. The primary contributors to the climate crisis do not necessarily face its most severe consequences, and much of the global population aspires to a level of wellbeing incompatible with the planet's resources. These aspects, focusing on the environmental pillar, will be discussed in depth.