A growing body of research confirms that spiritual practices are often linked to enhanced wellbeing, resilience, and social connectedness. However, the specific impact of Catholic devotions—such as the Rosary, Eucharistic adoration, personal prayer, and processions—remains underexplored. This study addresses this gap through a mixed-methods design combining survey data (N = 316) and qualitative analysis of 168 testimonials on Eucharistic adoration. Quantitative results show high levels of personal spirituality and belief in the transformative power of faith, with wellbeing and empathy positively correlated and both negatively associated with spiritual struggle. Notably, deeper devotional engagement—especially in personal prayer and adoration—was linked to both greater flourishing and increased spiritual struggle, suggesting that intense spiritual life may surface inner tensions alongside its benefits. Decision tree models revealed that openness, meaning, and communal anchoring predicted wellbeing and empathy, while solitary engagement and lack of meaning predicted struggle. Thematic analysis of adoration experiences highlighted peace, trust, clarity, and joy, yet also revealed that participants often brought emotional difficulty into their prayer. Together, the findings paint a complex picture: Catholic devotions promote wellbeing and empathy while also opening space for honest struggle. These results challenge stereotypes of devotionalism as passive or outdated, showing instead its depth, affective richness, and relevance for contemporary spiritual life.