In the context of his reflection on the Ignatian Exercises, Michel de Certeau associates the introductory text of the Four Weeks, "Principle and Foundation", with a "non-place", thus allowing human desire to detach oneself from every concrete wish, option, decision and place/scene imagined during the meditations. In doing so, he characterizes the spiritual and desiring subject in its fundamental ineffable singularity, which exceeds all kinds of objectifiable identifications. This does not mean that the spiritual journey of Christian mystics would generally end in pure negative nothingness. Rather, the mystical texts, which Certeau analyzes, in addition to vast geographical journeys, testify to the creation of a pluriform imaginative inner landscape in which desire can move playfully and find possibilities of delight. Referring primarily to his studies on Ignatian and Carmelite spirituality, the contribution examines how Certeau shapes the dynamics of desire and the creation of a subjective "interiority" in Christian mysticism by using spatial categories. The decisive role of imagination in spiritual practices will thereby be brought especially into focus.