The sensitivity of intraoperative frozen section (FS) is influenced by the experience of the surgeon requiring and by that of the pathologist delivering FS analysis. We analyzed FS performance in a secondary care hospital, sharing thyroid surgeon and pathology with the nearby university hospital.
Indications, results and consequences of all thyroid FS performed between 01.01.20201 and 31.12.2022 were critically reviewed.
FS was performed in 90 (26.5%) of 340 procedures. Malignancy was diagnosed in 21 (23.3%) of tumors and confirmed by final histology in all cases. In seven cases (10.1%) in which FS encountered no clear signs of malignancy a thyroid carcinoma was diagnosed by final histology. All tumors were follicular variant PTCs. In three cases no FS was performed but a thyroid carcinoma was diagnosed by final histology. Two-staged surgery was necessary in 10 (15.8%) carcinomas.
FS Sensitivity in a secodary care hospital sharing surgical and pathologic experience with a university hospital is 75% and mainly reduced by the prevalence of follicular variant PTC.