Incidence of post-operative hypocalcemia is still an important issue even in high volume center and in expert surgeon. Nevertheless the advance of new techinques, helping the surgeon in a better recognition and more precise sparing of parathyroid glands, leading to improved outcome for patients subjected to Total Thyroidectomy, post operative hypoparathyroidism and consequently hypocalcemia is still the most common complication.

We evaluated incidence and correlation between pre and post operative variables related to hypocalcemia values in patients subjected to thyroid surgery in the department of General Surgery of Ospedale di Circolo di Varese in the last three months with a six months follow-up. We created a prospective database comprehending pre-operative data, diagnosis, comorbidities, admission therapies and post operative data. We excluded patients showing other complications rather than post-operative hypocalcemia. We show our initial data

Out of 42 patients subjected to Total Thyroidectomy, 18 patients (42,9%) manifested transient hypocalcemia. No difference in BMI, comorbidities, pre-operative calcemia, pre-operative diagnosis, operative time and hemostasis devices were detected between hypocalcemic and non-hypocalcemic patients. The average length of hospitalization is 2,7 days in normocalcemic group versus 4,1 days in hypocalcemic patients (p< 0,001).

In larger series, even in our centre, hypocalcemia presents predictive factors which, in this more limited and new analysis, probably do not yet manifest. it is probable that even by extending the series, in high volume of thyroid surgery's centers, the correlation with predictive factors is increasingly less strong due to surgical experience.