O-188 - VALIDATION OF ARTERIO VENOUS ACCESS STAGE CLASSIFICATION (VAVASC): STUDY PROTOCOL AND PRELIMINARY RESULTS

TOPIC:
Vascular Access
AUTHORS:
Lawrie K. (Vascular Surgery, Cardiocenter, University Hospital Kralovske Vinohrady and 3rd faculty of Medicine, Charles University, Pragueue ~ Prague ~ Czech Republic) , O'Neill S. (Belfast City Hospital and Queen's University Belfast ~ Belfast ~ Ireland) , Waldauf P. (Department of Anesthesiology and Resuscitation, University Hospital Kralovske Vinohrady and 3rd faculty of Medicine, Charles University, Prague ~ Prague ~ Czech Republic) , Balaz P. (Vascular Surgery, Cardiocenter, University Hospital Kralovske Vinohrady and 3rd faculty of Medicine, Charles University, Pragueue ~ Prague ~ Czech Republic)
Introduction:
The VAVASC study (Validation of Arterio Venous Access Stage Classification) is a prospective, multicenter, international study with the aim to statistically validate AVAS (Arterio Venous Access Stage) classification. The AVAS classification system was developed in 2020 and it describes the vascular status of patients who are indicated for the creation of arteriovenous access on the upper limb. The classification simplifies the results of clinical examination and vascular mapping prior to vascular access surgery. The system also allows patients categorization that we find to be useful not only for further research purposes but also in daily clinical practice. The presentation aims to describe a study protocol and present the preliminary results.
Methods:
The observational, prospective, multicenter, international study started in March 2021 (NCT04796558). The basic demographic data, risk factors, vascular mapping parameters, and follow-up data, including AV access patency, failure, complications, and interventions are collected via an online platform that was created especially for this purpose. The outcome measures are the stage of AVAS, predicted arteriovenous access, final arteriovenous access that has been created, and patency of the arteriovenous access. The predictive models will be used for statistical analysis.
Results:
Currently, 360 patients from six centers (Brazil, the Czech Republic, Great Britain, Italy, Poland, and Slovakia) are recruited and are undergoing evaluation. The most frequent AVAS stages are 1ABCD (25%), 1CD (26%), 1C (18%) and 1BCD (9%). The most common AV accesses are autogenous radiocephalic fistula (43%), autogenous brachiocephalic fistula (38%), and autogenous brachiobasilic fistula (9%). All involved health care professionals apply the classification system correctly with good understanding and the number of recruited patients is constantly increasing.
Conclusion:
The preliminary data indicates that AVAS classification seems to be a good prediction tool for vascular access creation. The study is still open for collaboration with other centers that can register via our website - www.vavasc.com.
References:
Lawrie K., O'Neill S, Waldauf P. Balaz P. VAVASC study: Clinical trial protocol. J Vasc Access. 2021 Sep 2:11297298211042677. doi: 10.1177/11297298211042677 Balaz P., Hanko J., Magowan H., Masengu A., Lawrie K. and O'Neill S. The arteriovenous access stage (AVAS) classification. CKJ, 2020; 1-5. doi: 10.1093/ckj/sfaa189
ATTACHMENTS: