Transhumanism envisions a radical transformation of the human condition through technology, aiming to enhance physical, cognitive, and emotional capacities beyond biological limits. Such a project raises profound moral and theological questions, particularly in relation to the Catholic understanding of the human person as a creature endowed with intrinsic dignity and a transcendent destiny. This paper explores the tension between the Promethean drive to redesign the human being and the moral principles that safeguard its sacredness and integrity. Focusing on biotechnological and digital enhancement projects, from artificial intelligence to genetic engineering, it seeks to assess whether a form of "religious transhumanism" might be possible: one that reconciles technological progress with the Catholic vision of creation, grace, and human flourishing. The aim is to open a dialogue between faith and innovation, imagining a future where technology becomes a means of cooperation with, rather than substitution for, divine creation.