This paper seeks, first of all, to identify common theological horizons, especially around pneumatology: the Orthodox understanding of the Spirit as the principle of communion and sanctification, and the Pentecostal experience centered on the gifts and charismatic life. It then addresses the tensions and difficult issues, such as biblical hermeneutics, ecclesiology, and the relationship between experience and doctrine, which have generated significant distances between the two traditions. The analysis is situated within the particularities of the Latin American context, marked by social, cultural, and religious dynamics that demand a practical ecumenism oriented toward mission and social justice. Finally, it is proposed that dialogue from the Spirit constitutes not only a theological framework but also a praxis that fosters unity in diversity through spaces of prayer, reflection, and pastoral cooperation. This approach seeks to contribute to the renewal of ecumenism in Latin America, offering keys for a communion that is both faithful to tradition and open to the transformative action of the Spirit.