My contribution aims to present the film production activities carried out by the Pontifical Institute for Foreign Missions (P.I.M.E.) in Milan, a missionary institute founded in Milan in 1850 and now active in 19 countries around the world. In the 1950s, the Institute decided to promote its activities through audiovisual media. Over the years, the Institute increased its film production and distribution, directly involving both professionals in the sector and the missionaries themselves, and subsequently creating a dedicated production, post-production, and distribution center at its Milan headquarters, which remained active until 2004. PIME's audiovisual production is characterized by a great diversity of content and approaches to the audiovisual medium, both in terms of subject matter, linked to the different mission territories and contexts of activity, and in terms of narrative style (documentary, journalistic, film, etc.). This diversity is also reflected in the production media, which include 16, 8 and Super 8 mm film, magnetic tape (Betacam, Betamax, VHS, etc.), and digital media. The material, currently stored at the General and Photographic Archive in Milan, has recently been the subject of a reorganization and inventory project with the aim of making it accessible to users once again and enhancing its many potential uses. During the intervention, I will attempt to highlight the similarities and specificities related to PIME's audiovisual production, especially with regard to the broader Catholic and missionary context in Italy in the second half of the 20th century.