Details a patient with a mid-gland pancreatic insulinoma who underwent a central pancreatectomy (CP) without anastomoses. The report highlights the advantages of this approach in preserving endocrine function while effectively treating benign and low-grade malignant lesions of the pancreas

Traditional resections for mid-pancreatic lesions often lead to significant loss of normal parenchyma and potential pancreatic endocrine and exocrine insufficiency. Central pancreatectomy (CP) is a parenchyma-sparing surgical option for lesions in the neck and proximal body of the pancreas, preserving distal pancreas, endocrine functions, and spleen.A 50-year-old patient presented with recurrent hypoglycemic symptoms, transient neurological episodes, and weight gain. Imaging revealed a well-defined neuroendocrine tumor in the mid-body of the pancreas. Surgical intervention involved a bilateral subcostal incision, visualizing and dissecting the pancreas, identifying the lesion, and performing a central pancreatectomy. The histopathology confirmed a well-differentiated neuroendocrine tumor (grade 1) without lymphovascular invasion.

patient's blood sugar levels returned to normal post-surgery. Initially, there was a minimal pancreatic leak requiring re-exploration and the placement of an additional drain. The patient recovered gradually, with the drain removed over subsequent weeks.literature review summarizing outcomes and complications from various types of pancreatic anastomoses included

Central pancreatectomy (CP) is an effective approach for preserving pancreatic function, especially for lesions smaller than 2cm in the body of the pancreas. Omitting a pancreatico-enteric anastomosis during CP might reduce complications like pancreatic fistulas and preserve exocrine function. The conclusion emphasized that CP without anastomosis reduces morbidity and hospital stay compared to CP with anastomosis, showing efficacy in treating smaller lesions without compromising pancreatic function significantly.