COULD ULTRASONOGRAPHY BE USED AS A SINGLE IMAGING METHOD FOR PARATHYROID ADENOMA LOCALISATION IN PRIMARY HYPERPARATHYROIDISM? CERRAHPASA EXPERIENCE

AUTHORS:
S. Soylu Yaliman (Istanbul, Turkey) , S. Teksoz (Istanbul, Turkey) , E. Peker (Istanbul, Turkey)
Background:
We aimed to evaluate the role of neck ultrasonography alone for preoperative localization of parathyroid adenoma due to primary hyperparathyroidism.
Methods:
We analyzed 117 patients (87 female and 30 male patients, mean age: 53.8 years) who had parathyroidectomy due to primary hyperparathyroidism and had only preoperative neck ultrasonography (USG) as the localisation study. The preoperative radiological findings were correlated with operative and pathological results.
Results:
124 parathyroidectomies were done in 117 patients who had preoperative neck USG alone as imaging done by a single radiologist experienced in the field of head and neck ultrasonography. 6 patients had parathyroid gland in carotid sheath and the rest had parathyroid glands in cervical region. With USG, in 3 patients, localisation side was right but upper or lower region was identified incorrectly. In 3 cases, parathyroid hormone (PTH) and calcium levels were high postoperatively. In 2 of these 3 cases, parathyroid glands were hyperplastic and in 1, no parathyroid gland was found. 4 double adenomas were found and in all 4 cases one gland was hyperplastic and the other parathyroid gland was normal. In these 4 cases, only in 1 patient, PTH and calcium did not decline to normal levels postoperatively. The sensitivitiy, specifity, positive predictive value and negative predictive value were 97.4%, 80%, 93.3%, 60% for neck ultrasonography respectively.
Conclusions:
Neck ultrasonography alone by an experienced radiologist is effective in localisation of parathyroid adenomas in primary hyperparathyroidism.