The aim of this study is to review the experience of a hospital center in parathyroid surgery.

This was a retrospective, single-center study of patients who underwent parathyroidectomy between 2013 and 2022 at our center. Clinical and demographic data from the patients' medical records were used.

Of the 48 patients involved, 47 had primary hyperparathyroidism, and 1 had secondary hyperparathyroidism. 90% of the patients were female, and the average age at the time of surgery was 61 years. At the time of diagnosis, 75% of patients had symptoms of the disease, including nephrolithiasis in 61 % of patients and osteopathy/osteoporosis in more than half of the patients. The median pre-op and post-op PTH levels were 141.4 [elevated] (range 79-751 pg/ml) and 61.0 [normal] (range 23-391 pg/ml), respectively. 41 patients (86%) had a surgical specimen compatible with parathyroid adenoma, 4 patients (8%) had hyperplasia of the thyroid gland, and 3 patients (6%) had no parathyroid tissue in the histopathological analysis. There were no cases of parathyroid gland carcinoma. Post-operative complications affected 5 patients (10%), with transient hypocalcemia in 4 patients and transient vocal cord paresis in 1 patient. No pain or wound-related complications were noted, and there were no mortalities. 44 patients (92%) met the cure criteria, while two experienced recurrent hyperparathyroidism, and two persistent hyperparathyroidism. Follow‐up duration varied from six months to 24 months.

Parathyroidectomy is a safe treatment for hyperparathyroidism in our hospital center. Considering the low incidence of hyperparathyroidism, our sample of 48 patients was meaningful to evaluate the outcome of parathyroid surgery.